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Management of Amavata with ‘Amrita Ghrita’: A clinical study

Amavata is a disease caused due to the vitiation or aggravation of Vayu associated with Ama. Vitiated Vayu circulates the Ama all over the body through Dhamanies, takes shelter in the Shleshma Sthana (Amashaya, Sandhi, etc.), producing symptoms such as stiffness, swelling, and tenderness in small an...

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Autores principales: Lekurwale, P. S., Pandey, Kamlesh, Yadaiah, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202259/
https://www.ncbi.nlm.nih.gov/pubmed/22048534
http://dx.doi.org/10.4103/0974-8520.82033
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author Lekurwale, P. S.
Pandey, Kamlesh
Yadaiah, P.
author_facet Lekurwale, P. S.
Pandey, Kamlesh
Yadaiah, P.
author_sort Lekurwale, P. S.
collection PubMed
description Amavata is a disease caused due to the vitiation or aggravation of Vayu associated with Ama. Vitiated Vayu circulates the Ama all over the body through Dhamanies, takes shelter in the Shleshma Sthana (Amashaya, Sandhi, etc.), producing symptoms such as stiffness, swelling, and tenderness in small and big joints, making a person lame. The symptoms of Amavata are identical to rheumatism, which include rheumatoid arthritis and rheumatic fever. It is observed that rheumatism is an autoimmune disorder, which is among the collagen disorders having strong and significant parlance with Amavata. Various drug trials were already carried out on Amavata, yet there is a lacuna in the management of Amavata. Hence, in the present clinical study, 28 patients were selected and kept on ‘Amrita Ghrita’. All the patients were investigated for complete blood count (CBC), rheumatoid arthritis (RA) titer, Antistreptolysin O (ASO) titer, C-reactive protein (CRP) titer, platelet count, urine routine, and microscopic, before and after treatment. The collected data was distributed according to age, sex, and prakruti, and a t-test was applied for the clinical assessment of the subjective and objective parameters of ‘Amrita Ghrita,’ and it has shown significant reduction in the positivity of the RA titer (t > 5.09, at the 0.001% level), ASO titer (t > 4.08, at the 0.001% level), and CRP titer (t > 4.82, at the 0.001% level), and weight gain (t > 5.12, at the 0.001% level), as also an increase in Hb% (t >9.22, at the 0.001% level), and platelet count (t> 5.90, at the 0.001% level), and decrease in ESR (t > 9.70, at the 0.001% level).
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spelling pubmed-32022592011-10-28 Management of Amavata with ‘Amrita Ghrita’: A clinical study Lekurwale, P. S. Pandey, Kamlesh Yadaiah, P. Ayu Clinical Research Amavata is a disease caused due to the vitiation or aggravation of Vayu associated with Ama. Vitiated Vayu circulates the Ama all over the body through Dhamanies, takes shelter in the Shleshma Sthana (Amashaya, Sandhi, etc.), producing symptoms such as stiffness, swelling, and tenderness in small and big joints, making a person lame. The symptoms of Amavata are identical to rheumatism, which include rheumatoid arthritis and rheumatic fever. It is observed that rheumatism is an autoimmune disorder, which is among the collagen disorders having strong and significant parlance with Amavata. Various drug trials were already carried out on Amavata, yet there is a lacuna in the management of Amavata. Hence, in the present clinical study, 28 patients were selected and kept on ‘Amrita Ghrita’. All the patients were investigated for complete blood count (CBC), rheumatoid arthritis (RA) titer, Antistreptolysin O (ASO) titer, C-reactive protein (CRP) titer, platelet count, urine routine, and microscopic, before and after treatment. The collected data was distributed according to age, sex, and prakruti, and a t-test was applied for the clinical assessment of the subjective and objective parameters of ‘Amrita Ghrita,’ and it has shown significant reduction in the positivity of the RA titer (t > 5.09, at the 0.001% level), ASO titer (t > 4.08, at the 0.001% level), and CRP titer (t > 4.82, at the 0.001% level), and weight gain (t > 5.12, at the 0.001% level), as also an increase in Hb% (t >9.22, at the 0.001% level), and platelet count (t> 5.90, at the 0.001% level), and decrease in ESR (t > 9.70, at the 0.001% level). Medknow Publications Pvt Ltd 2010 /pmc/articles/PMC3202259/ /pubmed/22048534 http://dx.doi.org/10.4103/0974-8520.82033 Text en © AYU (An International Quarterly Journal of Research in Ayurveda) http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Lekurwale, P. S.
Pandey, Kamlesh
Yadaiah, P.
Management of Amavata with ‘Amrita Ghrita’: A clinical study
title Management of Amavata with ‘Amrita Ghrita’: A clinical study
title_full Management of Amavata with ‘Amrita Ghrita’: A clinical study
title_fullStr Management of Amavata with ‘Amrita Ghrita’: A clinical study
title_full_unstemmed Management of Amavata with ‘Amrita Ghrita’: A clinical study
title_short Management of Amavata with ‘Amrita Ghrita’: A clinical study
title_sort management of amavata with ‘amrita ghrita’: a clinical study
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202259/
https://www.ncbi.nlm.nih.gov/pubmed/22048534
http://dx.doi.org/10.4103/0974-8520.82033
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