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A Novel Metagenomic Short-Chain Dehydrogenase/Reductase Attenuates Pseudomonas aeruginosa Biofilm Formation and Virulence on Caenorhabditis elegans
In Pseudomonas aeruginosa, the expression of a number of virulence factors, as well as biofilm formation, are controlled by quorum sensing (QS). N-Acylhomoserine lactones (AHLs) are an important class of signaling molecules involved in bacterial QS and in many pathogenic bacteria infection and host...
Autores principales: | Bijtenhoorn, Patrick, Mayerhofer, Hubert, Müller-Dieckmann, Jochen, Utpatel, Christian, Schipper, Christina, Hornung, Claudia, Szesny, Matthias, Grond, Stephanie, Thürmer, Andrea, Brzuszkiewicz, Elzbieta, Daniel, Rolf, Dierking, Katja, Schulenburg, Hinrich, Streit, Wolfgang R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202535/ https://www.ncbi.nlm.nih.gov/pubmed/22046268 http://dx.doi.org/10.1371/journal.pone.0026278 |
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