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Species-Specific Codon Context Rules Unveil Non-Neutrality Effects of Synonymous Mutations
BACKGROUND: Codon pair usage (codon context) is a species specific gene primary structure feature whose evolutionary and functional roles are poorly understood. The data available show that codon-context has direct impact on both translation accuracy and efficiency, but one does not yet understand h...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202573/ https://www.ncbi.nlm.nih.gov/pubmed/22046369 http://dx.doi.org/10.1371/journal.pone.0026817 |