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Novel Adiponectin Variants Identified in Type 2 Diabetic Patients Reveal Multimerization and Secretion Defects

ADIPOQ, encoding adiponectin, is a candidate gene for type 2 diabetes (T2D) identified by genome-wide linkage analyses with supporting evidence showing the protein function in sensitizing insulin actions. In an endeavor to characterize candidate genes causing T2D in Thai patients, we identified 10 n...

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Detalles Bibliográficos
Autores principales: Jungtrakoon, Prapaporn, Plengvidhya, Nattachet, Tangjittipokin, Watip, Chimnaronk, Sarin, Salaemae, Wanisa, Chongjaroen, Nalinee, Chanprasert, Kanjana, Sujjitjoon, Jatuporn, Srisawat, Chatchawan, Yenchitsomanus, Pa-thai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202584/
https://www.ncbi.nlm.nih.gov/pubmed/22046359
http://dx.doi.org/10.1371/journal.pone.0026792