Structural Basis for Broad Neutralization of Hepatitis C Virus Quasispecies

Monoclonal antibodies directed against hepatitis C virus (HCV) E2 protein can neutralize cell-cultured HCV and pseudoparticles expressing envelopes derived from multiple HCV subtypes. For example, based on antibody blocking experiments and alanine scanning mutagenesis, it was proposed that the AR3B...

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Detalles Bibliográficos
Autores principales: Lapierre, Pascal, Troesch, Myriam, Alvarez, Fernando, Soudeyns, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202596/
https://www.ncbi.nlm.nih.gov/pubmed/22046426
http://dx.doi.org/10.1371/journal.pone.0026981

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