Regulatory T Cells in Transplantation

T Regulatory cells (Treg) play an important role in the induction and maintenance of immunological tolerance to self and alloantigens. Recent findings in experimental transplant models have demonstrated that Treg can control acute and delayed allograft rejection. Preclinical attempts to use Treg as...

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Detalles Bibliográficos
Autor principal: Wood, K.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202641/
https://www.ncbi.nlm.nih.gov/pubmed/21839214
http://dx.doi.org/10.1016/j.transproceed.2011.06.050
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author Wood, K.J.
author_facet Wood, K.J.
author_sort Wood, K.J.
collection PubMed
description T Regulatory cells (Treg) play an important role in the induction and maintenance of immunological tolerance to self and alloantigens. Recent findings in experimental transplant models have demonstrated that Treg can control acute and delayed allograft rejection. Preclinical attempts to use Treg as a cellular therapy have been successfully undertaken demonstrating the safety and feasibility of such treatment, suggesting that they have therapeutic potential.
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spelling pubmed-32026412011-10-28 Regulatory T Cells in Transplantation Wood, K.J. Transplant Proc Review T Regulatory cells (Treg) play an important role in the induction and maintenance of immunological tolerance to self and alloantigens. Recent findings in experimental transplant models have demonstrated that Treg can control acute and delayed allograft rejection. Preclinical attempts to use Treg as a cellular therapy have been successfully undertaken demonstrating the safety and feasibility of such treatment, suggesting that they have therapeutic potential. Elsevier Science Inc 2011-07 /pmc/articles/PMC3202641/ /pubmed/21839214 http://dx.doi.org/10.1016/j.transproceed.2011.06.050 Text en © 2011 Elsevier Inc. https://creativecommons.org/licenses/by/4.0/ Open Access under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/) license
spellingShingle Review
Wood, K.J.
Regulatory T Cells in Transplantation
title Regulatory T Cells in Transplantation
title_full Regulatory T Cells in Transplantation
title_fullStr Regulatory T Cells in Transplantation
title_full_unstemmed Regulatory T Cells in Transplantation
title_short Regulatory T Cells in Transplantation
title_sort regulatory t cells in transplantation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202641/
https://www.ncbi.nlm.nih.gov/pubmed/21839214
http://dx.doi.org/10.1016/j.transproceed.2011.06.050
work_keys_str_mv AT woodkj regulatorytcellsintransplantation

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