Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008

A retrospective case review study of viper envenomations collected by the Marseille’s Poison Centre between 1996 and 2008 was performed. Results: 174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and s...

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Autores principales: de Haro, Luc, Glaizal, Mathieu, Tichadou, Lucia, Blanc-Brisset, Ingrid, Hayek-Lanthois, Maryvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202779/
https://www.ncbi.nlm.nih.gov/pubmed/22069534
http://dx.doi.org/10.3390/toxins1020100
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author de Haro, Luc
Glaizal, Mathieu
Tichadou, Lucia
Blanc-Brisset, Ingrid
Hayek-Lanthois, Maryvonne
author_facet de Haro, Luc
Glaizal, Mathieu
Tichadou, Lucia
Blanc-Brisset, Ingrid
Hayek-Lanthois, Maryvonne
author_sort de Haro, Luc
collection PubMed
description A retrospective case review study of viper envenomations collected by the Marseille’s Poison Centre between 1996 and 2008 was performed. Results: 174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and six (106) of the G2/G3 patients were treated with the antivenom Viperfav* (2.1+/-0.9 days in hospital), while 15 of them received symptomatic treatments only (plus one immediate death) (8.1+/-4 days in hospital, 2 of them died). The hospital stay was significantly reduced in the antivenom treated group (p < 0.001), and none of the 106 antivenom treated patients had immediate (anaphylaxis) or delayed (serum sickness) allergic reactions. Conclusion: Viperfav* antivenom was safe and effective for treating asp viper venom-induced toxicity.
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spelling pubmed-32027792011-11-08 Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008 de Haro, Luc Glaizal, Mathieu Tichadou, Lucia Blanc-Brisset, Ingrid Hayek-Lanthois, Maryvonne Toxins (Basel) Article A retrospective case review study of viper envenomations collected by the Marseille’s Poison Centre between 1996 and 2008 was performed. Results: 174 cases were studied (52 grade 1 = G1, 90 G2 and 32 G3). G1 patients received symptomatic treatments (average hospital stay 0.96 day). One hundred and six (106) of the G2/G3 patients were treated with the antivenom Viperfav* (2.1+/-0.9 days in hospital), while 15 of them received symptomatic treatments only (plus one immediate death) (8.1+/-4 days in hospital, 2 of them died). The hospital stay was significantly reduced in the antivenom treated group (p < 0.001), and none of the 106 antivenom treated patients had immediate (anaphylaxis) or delayed (serum sickness) allergic reactions. Conclusion: Viperfav* antivenom was safe and effective for treating asp viper venom-induced toxicity. Molecular Diversity Preservation International 2009-11-24 /pmc/articles/PMC3202779/ /pubmed/22069534 http://dx.doi.org/10.3390/toxins1020100 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
de Haro, Luc
Glaizal, Mathieu
Tichadou, Lucia
Blanc-Brisset, Ingrid
Hayek-Lanthois, Maryvonne
Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008
title Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008
title_full Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008
title_fullStr Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008
title_full_unstemmed Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008
title_short Asp Viper (Vipera aspis) Envenomation: Experience of the Marseille Poison Centre from 1996 to 2008
title_sort asp viper (vipera aspis) envenomation: experience of the marseille poison centre from 1996 to 2008
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202779/
https://www.ncbi.nlm.nih.gov/pubmed/22069534
http://dx.doi.org/10.3390/toxins1020100
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AT blancbrissetingrid aspviperviperaaspisenvenomationexperienceofthemarseillepoisoncentrefrom1996to2008
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