Transcriptional activity regulates alternative cleavage and polyadenylation

Genes containing multiple pre-mRNA cleavage and polyadenylation sites, or polyA sites, express mRNA isoforms with variable 3′ untranslated regions (UTRs). By systematic analysis of human and mouse transcriptomes, we found that short 3′UTR isoforms are relatively more abundant when genes are highly e...

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Detalles Bibliográficos
Autores principales: Ji, Zhe, Luo, Wenting, Li, Wencheng, Hoque, Mainul, Pan, Zhenhua, Zhao, Yun, Tian, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202805/
https://www.ncbi.nlm.nih.gov/pubmed/21952137
http://dx.doi.org/10.1038/msb.2011.69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202805/
https://www.ncbi.nlm.nih.gov/pubmed/21952137
http://dx.doi.org/10.1038/msb.2011.69

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