Cargando…
From Toxins Targeting Ligand Gated Ion Channels to Therapeutic Molecules
Ligand-gated ion channels (LGIC) play a central role in inter-cellular communication. This key function has two consequences: (i) these receptor channels are major targets for drug discovery because of their potential involvement in numerous human brain diseases; (ii) they are often found to be the...
Autores principales: | Nasiripourdori, Adak, Taly, Valérie, Grutter, Thomas, Taly, Antoine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202823/ https://www.ncbi.nlm.nih.gov/pubmed/22069709 http://dx.doi.org/10.3390/toxins3030260 |
Ejemplares similares
-
Evolution of Pentameric Ligand-Gated Ion Channels: Pro-Loop Receptors
por: Jaiteh, Mariama, et al.
Publicado: (2016) -
Allosteric regulation of pentameric ligand-gated ion channels: An emerging mechanistic perspective
por: Taly, Antoine, et al.
Publicado: (2014) -
Long distance effect on ligand-gated ion channels extracellular domain may affect interactions with the intracellular machinery
por: Garret, Maurice, et al.
Publicado: (2014) -
Optical control of PIEZO1 channels
por: Peralta, Francisco Andrés, et al.
Publicado: (2023) -
Ligand-Gated Ion Channels: Prognostic and Therapeutic Implications for Gliomas
por: Hey, Grace, et al.
Publicado: (2023)