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The Biology of the Cytolethal Distending Toxins
The cytolethal distending toxins (CDTs), produced by a variety of Gram-negative pathogenic bacteria, are the first bacterial genotoxins described, since they cause DNA damage in the target cells. CDT is an A-B(2) toxin, where the CdtA and CdtC subunits are required to mediate the binding on the surf...
Autores principales: | Guerra, Lina, Cortes-Bratti, Ximena, Guidi, Riccardo, Frisan, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202825/ https://www.ncbi.nlm.nih.gov/pubmed/22069704 http://dx.doi.org/10.3390/toxins3030172 |
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