Mechanism of Lethal Toxin Neutralization by a Human Monoclonal Antibody Specific for the PA(20) Region of Bacillus anthracis Protective Antigen

The primary immunogenic component of the currently approved anthrax vaccine is the protective antigen (PA) unit of the binary toxin system. PA-specific antibodies neutralize anthrax toxins and protect against infection. Recent research has determined that in humans, only antibodies specific for part...

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Detalles Bibliográficos
Autores principales: Reason, Donald, Liberato, Justine, Sun, Jinying, Camacho, Jessica, Zhou, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202870/
https://www.ncbi.nlm.nih.gov/pubmed/22069752
http://dx.doi.org/10.3390/toxins3080979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202870/
https://www.ncbi.nlm.nih.gov/pubmed/22069752
http://dx.doi.org/10.3390/toxins3080979

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