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Anthrax Lethal Toxin-Induced Gene Expression Changes in Mouse Lung

A major virulence factor of Bacillus anthracis is the anthrax Lethal Toxin (LeTx), a bipartite toxin composed of Protective Antigen and Lethal Factor. Systemic administration of LeTx to laboratory animals leads to death associated with vascular leakage and pulmonary edema. In this study, we investig...

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Detalles Bibliográficos
Autores principales: Dumas, Eric K., Cox, Philip M., Fullenwider, Charles O’Connor, Nguyen, Melissa, Centola, Michael, Frank, Mark Barton, Dozmorov, Igor, James, Judith A., Farris, A. Darise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202878/
https://www.ncbi.nlm.nih.gov/pubmed/22039574
http://dx.doi.org/10.3390/toxins3091111