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Evaluation of (18)F-nifene binding to α4β2 nicotinic receptors in the rat brain using microPET imaging

MicroPET imaging studies using (18)F-nifene, a new positron emission tomography (PET) radiotracer for nicotinic acetylcholinergic receptors (nAChR) α4β2 receptors in rats, have been carried out. Rats were imaged for 90 min after intravenous injection of (18)F-nifene (0.8 to 1 mCi), and binding poten...

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Detalles Bibliográficos
Autores principales: Kant, Ritu, Constantinescu, Cristian C, Parekh, Puja, Pandey, Suresh K, Pan, Min-Liang, Easwaramoorthy, Balu, Mukherjee, Jogeshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203019/
https://www.ncbi.nlm.nih.gov/pubmed/22039577
http://dx.doi.org/10.1186/2191-219X-1-6