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Unbiased Simulations Reveal the Inward-Facing Conformation of the Human Serotonin Transporter and Na(+) Ion Release

Monoamine transporters are responsible for termination of synaptic signaling and are involved in depression, control of appetite, and anxiety amongst other neurological processes. Despite extensive efforts, the structures of the monoamine transporters and the transport mechanism of ions and substrat...

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Detalles Bibliográficos
Autores principales:	Koldsø, Heidi, Noer, Pernille, Grouleff, Julie, Autzen, Henriette Elisabeth, Sinning, Steffen, Schiøtt, Birgit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203053/ https://www.ncbi.nlm.nih.gov/pubmed/22046120 http://dx.doi.org/10.1371/journal.pcbi.1002246

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