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Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes

BACKGROUND: Prolonged alcohol consumption is a significant co-factor in the progression of chronic viral infections including hepatitis C and HIV, which are both single-stranded RNA viruses. Toll like receptor 8 (TLR8), a pattern recognition receptor expressed in monocytes, senses viral single stran...

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Detalles Bibliográficos
Autores principales:	Pang, Maoyin, Bala, Shashi, Kodys, Karen, Catalano, Donna, Szabo, Gyongyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203086/ https://www.ncbi.nlm.nih.gov/pubmed/21962237 http://dx.doi.org/10.1186/1471-2172-12-55

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