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A novel splice variant of the stem cell marker LGR5/GPR49 is correlated with the risk of tumor-related death in soft-tissue sarcoma patients

BACKGROUND: The human leucine-rich, repeat-containing G protein-coupled receptor (LGR) 5, also called GPR49, is a marker of stem cells in adult intestinal epithelium, stomach and hair follicles. LGR5/GPR49 is overexpressed in tumors of the colon, ovary and liver and in basal cell carcinomas. Moreove...

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Detalles Bibliográficos
Autores principales:	Rot, Swetlana, Taubert, Helge, Bache, Matthias, Greither, Thomas, Würl, Peter, Eckert, Alexander W, Schubert, Johannes, Vordermark, Dirk, Kappler, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203099/ https://www.ncbi.nlm.nih.gov/pubmed/21978106 http://dx.doi.org/10.1186/1471-2407-11-429

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