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Whole-exome sequencing of DNA from peripheral blood mononuclear cells (PBMC) and EBV-transformed lymphocytes from the same donor

BACKGROUND: The creation of lymphoblastoid cell lines (LCLs) through Epstein-Barr virus (EBV) transformation of B-lymphocytes can result in a valuable biomaterial for cell biology research and a renewable source of DNA. While LCLs have been used extensively in cellular and genetic studies, the proce...

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Detalles Bibliográficos
Autores principales: Londin, Eric R, Keller, Margaret A, D'Andrea, Michael R, Delgrosso, Kathleen, Ertel, Adam, Surrey, Saul, Fortina, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203102/
https://www.ncbi.nlm.nih.gov/pubmed/21943378
http://dx.doi.org/10.1186/1471-2164-12-464