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Penicillin Binding Proteins as Danger Signals: Meningococcal Penicillin Binding Protein 2 Activates Dendritic Cells through Toll-Like Receptor 4

Neisseria meningitidis is a human pathogen responsible for life-threatening inflammatory diseases. Meningococcal penicillin-binding proteins (PBPs) and particularly PBP2 are involved in bacterial resistance to β-lactams. Here we describe a novel function for PBP2 that activates human and mouse dendr...

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Detalles Bibliográficos
Autores principales:	Hill, Marcelo, Deghmane, Ala-Eddine, Segovia, Mercedes, Zarantonelli, Maria Leticia, Tilly, Gaëlle, Blancou, Philippe, Bériou, Gaëlle, Josien, Régis, Anegon, Ignacio, Hong, Eva, Ruckly, Corinne, Antignac, Aude, Ghachi, Meriem El, Boneca, Ivo Gomperts, Taha, Muhamed-Kheir, Cuturi, Maria Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203111/ https://www.ncbi.nlm.nih.gov/pubmed/22046231 http://dx.doi.org/10.1371/journal.pone.0023995

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