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Elucidation of the ATP7B N-Domain Mg(2+)-ATP Coordination Site and Its Allosteric Regulation
The diagnostic of orphan genetic disease is often a puzzling task as less attention is paid to the elucidation of the pathophysiology of these rare disorders at the molecular level. We present here a multidisciplinary approach using molecular modeling tools and surface plasmonic resonance to study t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203118/ https://www.ncbi.nlm.nih.gov/pubmed/22046264 http://dx.doi.org/10.1371/journal.pone.0026245 |