Anti-GBM Glomerulonephritis Involves IL-1 but Is Independent of NLRP3/ASC Inflammasome-Mediated Activation of Caspase-1

IL-1β and IL-18 are proinflammatory cytokines that contribute to renal immune complex disease, but whether IL-1β and IL-18 are mediators of intrinsic glomerular inflammation is unknown. In contrast to other cytokines the secretion of IL-1β and IL-18 requires a second stimulus that activates the infl...

Descripción completa

Detalles Bibliográficos
Autores principales: Lichtnekert, Julia, Kulkarni, Onkar P., Mulay, Shrikant R., Rupanagudi, Khader Valli, Ryu, Mi, Allam, Ramanjaneyulu, Vielhauer, Volker, Muruve, Dan, Lindenmeyer, Maja T., Cohen, Clemens D., Anders, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203143/
https://www.ncbi.nlm.nih.gov/pubmed/22046355
http://dx.doi.org/10.1371/journal.pone.0026778

Ejemplares similares

Ejemplares similares