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Pyomelanin Formation in Aspergillus fumigatus Requires HmgX and the Transcriptional Activator HmgR but Is Dispensable for Virulence

The opportunistic human pathogenic fungus Aspergillus fumigatus is able to produce the dark brown pigment pyomelanin by degradation of L-tyrosine. Pyomelanin was shown to protect the fungus against reactive oxygen intermediates as well as cell wall disturbing compounds and is therefore assumed to pr...

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Detalles Bibliográficos
Autores principales:	Keller, Sophia, Macheleidt, Juliane, Scherlach, Kirstin, Schmaler-Ripcke, Jeannette, Jacobsen, Ilse D., Heinekamp, Thorsten, Brakhage, Axel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203155/ https://www.ncbi.nlm.nih.gov/pubmed/22046314 http://dx.doi.org/10.1371/journal.pone.0026604

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