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Loss of the α2β1 Integrin Alters Human Papilloma Virus-Induced Squamous Carcinoma Progression In Vivo and In Vitro

Expression of the α2β1 integrin, a receptor for collagens and laminin, is altered during tumor progression. Recent studies have linked polymorphisms in the α2 integrin gene with oral, squamous cell carcinoma (SCC). To determine the α2β1 integrin's role in SCC progression, we crossed α2-null mic...

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Detalles Bibliográficos
Autores principales: Tran, Thuy, Barlow, Brittney, O'Rear, Lynda, Jarvis, Brenda, Li, Zhengzhi, Dickeson, Kent, Dupont, William, Zutter, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203166/
https://www.ncbi.nlm.nih.gov/pubmed/22046385
http://dx.doi.org/10.1371/journal.pone.0026858