Histone Deacetylase 8 Is Required for Centrosome Cohesion and Influenza A Virus Entry

Influenza A virus (IAV) enters host cells by endocytosis followed by acid-activated penetration from late endosomes (LEs). Using siRNA silencing, we found that histone deacetylase 8 (HDAC8), a cytoplasmic enzyme, efficiently promoted productive entry of IAV into tissue culture cells, whereas HDAC1 s...

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Detalles Bibliográficos
Autores principales: Yamauchi, Yohei, Boukari, Heithem, Banerjee, Indranil, Sbalzarini, Ivo F., Horvath, Peter, Helenius, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203190/
https://www.ncbi.nlm.nih.gov/pubmed/22046129
http://dx.doi.org/10.1371/journal.ppat.1002316

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