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Kinetics of the viral cycle influence pharmacodynamics of antiretroviral therapy
BACKGROUND: More and more antiretroviral therapies are being developed for treatment of HIV infection. The in-vivo efficacy of these drugs is commonly predicted based on in-vitro measures of antiviral effect. One primary in-vitro measure is the IC50, the amount of drug required for 50% inhibition of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203257/ https://www.ncbi.nlm.nih.gov/pubmed/21910865 http://dx.doi.org/10.1186/1745-6150-6-42 |