A Novel Nuclear Role for the Vav3 Nucleotide Exchange Factor in Androgen Receptor Coactivation in Prostate Cancer

Increased androgen receptor (AR) transcriptional activity mediated by coactivator proteins may drive castration resistant prostate cancer (CRPC) growth. Vav3, a Rho GTPase guanine nucleotide exchange factor (GEF), is over-expressed in human prostate cancers particularly in models of CRPC progression...

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Detalles Bibliográficos
Autores principales: Rao, Shuyun, Lyons, Leah S., Fahrenholtz, Cale D., Wu, Fayi, Farooq, Amjad, Balkan, Wayne, Burnstein, Kerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203328/
https://www.ncbi.nlm.nih.gov/pubmed/21765461
http://dx.doi.org/10.1038/onc.2011.273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203328/
https://www.ncbi.nlm.nih.gov/pubmed/21765461
http://dx.doi.org/10.1038/onc.2011.273

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