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Multi-objective optimization of enzyme manipulations in metabolic networks considering resilience effects
BACKGROUND: Improving the synthesis rate of desired metabolites in metabolic systems is one of the main tasks in metabolic engineering. In the last decade, metabolic engineering approaches based on the mathematical optimization have been used extensively for the analysis and manipulation of metaboli...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203348/ https://www.ncbi.nlm.nih.gov/pubmed/21929795 http://dx.doi.org/10.1186/1752-0509-5-145 |