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Quantitative utilization of prior biological knowledge in the Bayesian network modeling of gene expression data

BACKGROUND: Bayesian Network (BN) is a powerful approach to reconstructing genetic regulatory networks from gene expression data. However, expression data by itself suffers from high noise and lack of power. Incorporating prior biological knowledge can improve the performance. As each type of prior...

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Detalles Bibliográficos
Autores principales: Gao, Shouguo, Wang, Xujing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203352/
https://www.ncbi.nlm.nih.gov/pubmed/21884587
http://dx.doi.org/10.1186/1471-2105-12-359