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Quantitative utilization of prior biological knowledge in the Bayesian network modeling of gene expression data
BACKGROUND: Bayesian Network (BN) is a powerful approach to reconstructing genetic regulatory networks from gene expression data. However, expression data by itself suffers from high noise and lack of power. Incorporating prior biological knowledge can improve the performance. As each type of prior...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203352/ https://www.ncbi.nlm.nih.gov/pubmed/21884587 http://dx.doi.org/10.1186/1471-2105-12-359 |