Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase Inhibitors

[Image: see text] Cinnamaldehyde derivatives were synthesized in good to excellent yields in one step by a mild and selective, base-free palladium(II)-catalyzed oxidative Heck reaction starting from acrolein and various arylboronic acids. Prepared α,β-unsaturated aldehydes were used for synthesis of...

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Autores principales: Nordqvist, Anneli, Björkelid, Christofer, Andaloussi, Mounir, Jansson, Anna M., Mowbray, Sherry L., Karlén, Anders, Larhed, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203620/
https://www.ncbi.nlm.nih.gov/pubmed/21936546
http://dx.doi.org/10.1021/jo201715x

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