FGF/FGFR Signaling Coordinates Skull Development by Modulating Magnitude of Morphological Integration: Evidence from Apert Syndrome Mouse Models

The fibroblast growth factor and receptor system (FGF/FGFR) mediates cell communication and pattern formation in many tissue types (e.g., osseous, nervous, vascular). In those craniosynostosis syndromes caused by FGFR1-3 mutations, alteration of signaling in the FGF/FGFR system leads to dysmorpholog...

Descripción completa

Detalles Bibliográficos
Autores principales: Martínez-Abadías, Neus, Heuzé, Yann, Wang, Yingli, Jabs, Ethylin Wang, Aldridge, Kristina, Richtsmeier, Joan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203899/
https://www.ncbi.nlm.nih.gov/pubmed/22053191
http://dx.doi.org/10.1371/journal.pone.0026425

Ejemplares similares

Ejemplares similares