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The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH

The hypoxia-inducible factor (HIF) is a master regulator of the cellular response to hypoxia. Its levels and activity are controlled by dioxygenases called prolyl-hydroxylases and factor inhibiting HIF (FIH). To activate genes, HIF has to access sequences in DNA that are integrated in chromatin. It...

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Detalles Bibliográficos
Autores principales:	Melvin, Andrew, Mudie, Sharon, Rocha, Sonia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204077/ https://www.ncbi.nlm.nih.gov/pubmed/21900490 http://dx.doi.org/10.1091/mbc.E11-02-0163

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