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The Clathrin-Binding Domain of CALM-AF10 Alters the Phenotype of Myeloid Neoplasms in Mice

The PICALM (CALM) gene, whose product is involved in clathrin-mediated endocytosis, has been identified in two recurring chromosomal translocations, involving either MLL or MLLT10 (AF10). We developed a mouse model of CALM-AF10(+) leukemia to examine the hypothesis that disruption of endocytosis con...

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Detalles Bibliográficos
Autores principales:	Stoddart, Angela, Tennant, Thelma R., Fernald, Anthony A., Anastasi, John, Brodsky, Frances, Le Beau, Michelle M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204175/ https://www.ncbi.nlm.nih.gov/pubmed/21706055 http://dx.doi.org/10.1038/onc.2011.251

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