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HIV-1 transgene expression in rats induces differential expression of tumor necrosis factor alpha and zinc transporters in the liver and the lung

BACKGROUND: Highly effective antiviral treatment can suppress HIV-1 infection, but the chronic effects of HIV-1-related viral proteins, including gp120 and Tat, on organs such as the lungs can be damaging. HIV-1 transgenic rodent models are useful for studying the systemic effects of these proteins...

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Detalles Bibliográficos
Autores principales: Joshi, Pratibha C, Guidot, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204218/
https://www.ncbi.nlm.nih.gov/pubmed/21978457
http://dx.doi.org/10.1186/1742-6405-8-36