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High sensitivity of an ELISA kit for detection of the gamma-isoform of 14-3-3 proteins: usefulness in laboratory diagnosis of human prion disease
BACKGROUND: The gamma-isoform of the 14-3-3 protein (14-3-3 gamma) is expressed in neurons, and could be a specific marker for neuronal damage. This protein has been reported as a detectable biomarker, especially in the cerebrospinal fluid (CSF) of Creutzfeldt-Jakob disease (CJD) patients by Western...
Autores principales: | Matsui, Yuki, Satoh, Katsuya, Miyazaki, Toshiaki, Shirabe, Susumu, Atarashi, Ryuichiro, Mutsukura, Kazuo, Satoh, Akira, Kataoka, Yasufumi, Nishida, Noriyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204235/ https://www.ncbi.nlm.nih.gov/pubmed/21970675 http://dx.doi.org/10.1186/1471-2377-11-120 |
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