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Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders
BACKGROUND: Recent studies suggest that the pathogenic process in neurodegenerative disorders may disrupt mature neuronal circuitries and neurogenesis in the adult brain. Abnormal activation of CDK5 is associated with neurodegenerative disorders, and recently a critical role for CDK5 in adult neurog...
Autores principales: | Crews, Leslie, Ruf, Rebecca, Patrick, Christina, Dumaop, Wilmar, Trejo-Morales, Margarita, Achim, Cristian L, Rockenstein, Edward, Masliah, Eliezer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204248/ https://www.ncbi.nlm.nih.gov/pubmed/21943307 http://dx.doi.org/10.1186/1750-1326-6-67 |
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