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In vitro activities of novel 4-HPR derivatives on a panel of rhabdoid and other tumor cell lines
BACKGROUND: Rhabdoid tumors (RTs) are aggressive pediatric malignancies with poor prognosis. N-(4-hydroxy phenyl) retinamide (4-HPR or fenretinide) is a potential chemotherapeutic for RTs with activity correlated to its ability to down-modulate Cyclin D1. Previously, we synthesized novel halogen-sub...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204277/ https://www.ncbi.nlm.nih.gov/pubmed/21951911 http://dx.doi.org/10.1186/1475-2867-11-34 |