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Generation of a recombinant rabies Flury LEP virus carrying an additional G gene creates an improved seed virus for inactivated vaccine production

The rabies Flury Low Egg Passage virus (LEP) has been widely used as a seed virus to generate inactive vaccine. Here, we established a reverse genetic system for LEP and generated a recombinant LEP virus (rLEP-G) that carries two identical G genes. This recombinant virus showed similar properties to...

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Detalles Bibliográficos
Autores principales:	Tao, Lihong, Ge, Jinying, Wang, Xijun, Wen, Zhiyuan, Zhai, Hongyue, Hua, Tao, Zhao, Bolin, Kong, Dongni, Yang, Chinglai, Bu, Zhigao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204297/ https://www.ncbi.nlm.nih.gov/pubmed/21943337 http://dx.doi.org/10.1186/1743-422X-8-454

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