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Abrogation of contaminating RNA activity in HIV-1 Gag VLPs

BACKGROUND: HIV-1 Gag virus like particles (VLPs) used as candidate vaccines are regarded as inert particles as they contain no replicative nucleic acid, although they do encapsidate cellular RNAs. During HIV-1 Gag VLP production in baculovirus-based expression systems, VLPs incorporate the baculovi...

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Detalles Bibliográficos
Autores principales:	Valley-Omar, Ziyaad, Meyers, Ann E, Shephard, Enid G, Williamson, Anna-Lise, Rybicki, Edward P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204299/ https://www.ncbi.nlm.nih.gov/pubmed/21975161 http://dx.doi.org/10.1186/1743-422X-8-462

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