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Chronic imaging and manipulation of cells and vessels through a polished and reinforced thinned-skull
We present a method to form an optical window in the mouse skull that spans millimeters and is stable for months without inflammation of the brain. This enabled us to repeatedly image blood flow in cortical capillaries of awake animals and determine long-range correlations in speed. We further demon...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204312/ https://www.ncbi.nlm.nih.gov/pubmed/20966916 http://dx.doi.org/10.1038/nmeth.1530 |