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Recent Evolution of Surgical Treatment for Gastric Cancer in Korea
Gastric cancer is the most common malignancy and the incidence is steadily increasing in Korea. The principal treatment modality for gastric cancer is surgical extirpation of tumor along with draining lymph nodes. Gastrectomy with D2 lymph node dissection has been well established as a standard of s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Gastric Cancer Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204480/ https://www.ncbi.nlm.nih.gov/pubmed/22076195 http://dx.doi.org/10.5230/jgc.2011.11.1.1 |
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author | An, Ji Yeong Cheong, Jae-Ho Hyung, Woo Jin Noh, Sung Hoon |
author_facet | An, Ji Yeong Cheong, Jae-Ho Hyung, Woo Jin Noh, Sung Hoon |
author_sort | An, Ji Yeong |
collection | PubMed |
description | Gastric cancer is the most common malignancy and the incidence is steadily increasing in Korea. The principal treatment modality for gastric cancer is surgical extirpation of tumor along with draining lymph nodes. Gastrectomy with D2 lymph node dissection has been well established as a standard of surgery and improved the survival of gastric cancer patients. Recently, technological advances are drastically reshaping the landscape of surgical treatment of gastric cancer. One of the most notable trends is that minimal access surgery becomes dominating the treatment of early stage diseases. For advanced diseases, the standard access surgery is considered a reference treatment. Although there is a pilot study underway to evaluate the feasibility of the application of minimal access surgery to advanced gastric cancer (AGC), the evidence for oncological safety is not yet provided sufficiently. Based on the recent randomized controlled trials, the extent of surgery for AGC has re-defined as para-aortic lymph node dissection dose not add any survival benefit while increasing surgery-related morbidities. In addition, it is now accepted as a standard operation omitting unnecessary procedures such as splenectomy and/or distal pancreatectomy for prophylactic lymph node dissection. Conceptual and technical innovation has contributed to decreasing morbidity and mortality without impairing oncological safety. All these recent advances in the field of gastric cancer surgery would be concluded in maximizing therapeutic index for gastric cancer while improving quality of life. |
format | Online Article Text |
id | pubmed-3204480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | The Korean Gastric Cancer Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-32044802011-11-10 Recent Evolution of Surgical Treatment for Gastric Cancer in Korea An, Ji Yeong Cheong, Jae-Ho Hyung, Woo Jin Noh, Sung Hoon J Gastric Cancer Review Article Gastric cancer is the most common malignancy and the incidence is steadily increasing in Korea. The principal treatment modality for gastric cancer is surgical extirpation of tumor along with draining lymph nodes. Gastrectomy with D2 lymph node dissection has been well established as a standard of surgery and improved the survival of gastric cancer patients. Recently, technological advances are drastically reshaping the landscape of surgical treatment of gastric cancer. One of the most notable trends is that minimal access surgery becomes dominating the treatment of early stage diseases. For advanced diseases, the standard access surgery is considered a reference treatment. Although there is a pilot study underway to evaluate the feasibility of the application of minimal access surgery to advanced gastric cancer (AGC), the evidence for oncological safety is not yet provided sufficiently. Based on the recent randomized controlled trials, the extent of surgery for AGC has re-defined as para-aortic lymph node dissection dose not add any survival benefit while increasing surgery-related morbidities. In addition, it is now accepted as a standard operation omitting unnecessary procedures such as splenectomy and/or distal pancreatectomy for prophylactic lymph node dissection. Conceptual and technical innovation has contributed to decreasing morbidity and mortality without impairing oncological safety. All these recent advances in the field of gastric cancer surgery would be concluded in maximizing therapeutic index for gastric cancer while improving quality of life. The Korean Gastric Cancer Association 2011-03 2011-03-31 /pmc/articles/PMC3204480/ /pubmed/22076195 http://dx.doi.org/10.5230/jgc.2011.11.1.1 Text en Copyright © 2011 by The Korean Gastric Cancer Association http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article An, Ji Yeong Cheong, Jae-Ho Hyung, Woo Jin Noh, Sung Hoon Recent Evolution of Surgical Treatment for Gastric Cancer in Korea |
title | Recent Evolution of Surgical Treatment for Gastric Cancer in Korea |
title_full | Recent Evolution of Surgical Treatment for Gastric Cancer in Korea |
title_fullStr | Recent Evolution of Surgical Treatment for Gastric Cancer in Korea |
title_full_unstemmed | Recent Evolution of Surgical Treatment for Gastric Cancer in Korea |
title_short | Recent Evolution of Surgical Treatment for Gastric Cancer in Korea |
title_sort | recent evolution of surgical treatment for gastric cancer in korea |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204480/ https://www.ncbi.nlm.nih.gov/pubmed/22076195 http://dx.doi.org/10.5230/jgc.2011.11.1.1 |
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