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Recent Evolution of Surgical Treatment for Gastric Cancer in Korea

Gastric cancer is the most common malignancy and the incidence is steadily increasing in Korea. The principal treatment modality for gastric cancer is surgical extirpation of tumor along with draining lymph nodes. Gastrectomy with D2 lymph node dissection has been well established as a standard of s...

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Autores principales: An, Ji Yeong, Cheong, Jae-Ho, Hyung, Woo Jin, Noh, Sung Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Gastric Cancer Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204480/
https://www.ncbi.nlm.nih.gov/pubmed/22076195
http://dx.doi.org/10.5230/jgc.2011.11.1.1
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author An, Ji Yeong
Cheong, Jae-Ho
Hyung, Woo Jin
Noh, Sung Hoon
author_facet An, Ji Yeong
Cheong, Jae-Ho
Hyung, Woo Jin
Noh, Sung Hoon
author_sort An, Ji Yeong
collection PubMed
description Gastric cancer is the most common malignancy and the incidence is steadily increasing in Korea. The principal treatment modality for gastric cancer is surgical extirpation of tumor along with draining lymph nodes. Gastrectomy with D2 lymph node dissection has been well established as a standard of surgery and improved the survival of gastric cancer patients. Recently, technological advances are drastically reshaping the landscape of surgical treatment of gastric cancer. One of the most notable trends is that minimal access surgery becomes dominating the treatment of early stage diseases. For advanced diseases, the standard access surgery is considered a reference treatment. Although there is a pilot study underway to evaluate the feasibility of the application of minimal access surgery to advanced gastric cancer (AGC), the evidence for oncological safety is not yet provided sufficiently. Based on the recent randomized controlled trials, the extent of surgery for AGC has re-defined as para-aortic lymph node dissection dose not add any survival benefit while increasing surgery-related morbidities. In addition, it is now accepted as a standard operation omitting unnecessary procedures such as splenectomy and/or distal pancreatectomy for prophylactic lymph node dissection. Conceptual and technical innovation has contributed to decreasing morbidity and mortality without impairing oncological safety. All these recent advances in the field of gastric cancer surgery would be concluded in maximizing therapeutic index for gastric cancer while improving quality of life.
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spelling pubmed-32044802011-11-10 Recent Evolution of Surgical Treatment for Gastric Cancer in Korea An, Ji Yeong Cheong, Jae-Ho Hyung, Woo Jin Noh, Sung Hoon J Gastric Cancer Review Article Gastric cancer is the most common malignancy and the incidence is steadily increasing in Korea. The principal treatment modality for gastric cancer is surgical extirpation of tumor along with draining lymph nodes. Gastrectomy with D2 lymph node dissection has been well established as a standard of surgery and improved the survival of gastric cancer patients. Recently, technological advances are drastically reshaping the landscape of surgical treatment of gastric cancer. One of the most notable trends is that minimal access surgery becomes dominating the treatment of early stage diseases. For advanced diseases, the standard access surgery is considered a reference treatment. Although there is a pilot study underway to evaluate the feasibility of the application of minimal access surgery to advanced gastric cancer (AGC), the evidence for oncological safety is not yet provided sufficiently. Based on the recent randomized controlled trials, the extent of surgery for AGC has re-defined as para-aortic lymph node dissection dose not add any survival benefit while increasing surgery-related morbidities. In addition, it is now accepted as a standard operation omitting unnecessary procedures such as splenectomy and/or distal pancreatectomy for prophylactic lymph node dissection. Conceptual and technical innovation has contributed to decreasing morbidity and mortality without impairing oncological safety. All these recent advances in the field of gastric cancer surgery would be concluded in maximizing therapeutic index for gastric cancer while improving quality of life. The Korean Gastric Cancer Association 2011-03 2011-03-31 /pmc/articles/PMC3204480/ /pubmed/22076195 http://dx.doi.org/10.5230/jgc.2011.11.1.1 Text en Copyright © 2011 by The Korean Gastric Cancer Association http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
An, Ji Yeong
Cheong, Jae-Ho
Hyung, Woo Jin
Noh, Sung Hoon
Recent Evolution of Surgical Treatment for Gastric Cancer in Korea
title Recent Evolution of Surgical Treatment for Gastric Cancer in Korea
title_full Recent Evolution of Surgical Treatment for Gastric Cancer in Korea
title_fullStr Recent Evolution of Surgical Treatment for Gastric Cancer in Korea
title_full_unstemmed Recent Evolution of Surgical Treatment for Gastric Cancer in Korea
title_short Recent Evolution of Surgical Treatment for Gastric Cancer in Korea
title_sort recent evolution of surgical treatment for gastric cancer in korea
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204480/
https://www.ncbi.nlm.nih.gov/pubmed/22076195
http://dx.doi.org/10.5230/jgc.2011.11.1.1
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