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Tacrolimus related neurologic complication after pediatric kidney transplantation

Recently significant neurotoxicity has been reported with the use of carcineurin inhibitors. An 11-year-old-girl had undergone a transplantation of kidney from her mother. On post-operative day 12, hypertension, headache, and left motor weakness (grade I) suddenly occurred. The brain-magnetic resona...

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Autor principal: Kwun, Woo-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Surgical Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204550/
https://www.ncbi.nlm.nih.gov/pubmed/22066126
http://dx.doi.org/10.4174/jkss.2011.81.3.225
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author Kwun, Woo-Hyung
author_facet Kwun, Woo-Hyung
author_sort Kwun, Woo-Hyung
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description Recently significant neurotoxicity has been reported with the use of carcineurin inhibitors. An 11-year-old-girl had undergone a transplantation of kidney from her mother. On post-operative day 12, hypertension, headache, and left motor weakness (grade I) suddenly occurred. The brain-magnetic resonance imaging and magnetic resonance angiography showed acute cerebral infarction at subcortical white matter of the right hemisphere and multiple stenoses of both anterior cerebral artery and middle cerebral artery. While stopping tacrolimus treatment, we experienced clinical and radiological improvement. So, the neurological complications of this patient seem to have been caused by the use of tacrolimus.
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spelling pubmed-32045502011-11-07 Tacrolimus related neurologic complication after pediatric kidney transplantation Kwun, Woo-Hyung J Korean Surg Soc Case Report Recently significant neurotoxicity has been reported with the use of carcineurin inhibitors. An 11-year-old-girl had undergone a transplantation of kidney from her mother. On post-operative day 12, hypertension, headache, and left motor weakness (grade I) suddenly occurred. The brain-magnetic resonance imaging and magnetic resonance angiography showed acute cerebral infarction at subcortical white matter of the right hemisphere and multiple stenoses of both anterior cerebral artery and middle cerebral artery. While stopping tacrolimus treatment, we experienced clinical and radiological improvement. So, the neurological complications of this patient seem to have been caused by the use of tacrolimus. The Korean Surgical Society 2011-09 2011-09-26 /pmc/articles/PMC3204550/ /pubmed/22066126 http://dx.doi.org/10.4174/jkss.2011.81.3.225 Text en Copyright © 2011, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/3.0 Journal of the Korean Surgical Society is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kwun, Woo-Hyung
Tacrolimus related neurologic complication after pediatric kidney transplantation
title Tacrolimus related neurologic complication after pediatric kidney transplantation
title_full Tacrolimus related neurologic complication after pediatric kidney transplantation
title_fullStr Tacrolimus related neurologic complication after pediatric kidney transplantation
title_full_unstemmed Tacrolimus related neurologic complication after pediatric kidney transplantation
title_short Tacrolimus related neurologic complication after pediatric kidney transplantation
title_sort tacrolimus related neurologic complication after pediatric kidney transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204550/
https://www.ncbi.nlm.nih.gov/pubmed/22066126
http://dx.doi.org/10.4174/jkss.2011.81.3.225
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