Cargando…
Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection
PURPOSE: To analyze the outcomes of laparoscopic liver resection compared with open liver resection in patients with hepatocellular carcinoma (HCC). METHODS: Between July 2005 and December 2009, 26 consecutive patients with HCC underwent a pure laparoscopic liver resection, and data from this group...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Surgical Society
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204693/ https://www.ncbi.nlm.nih.gov/pubmed/22066068 http://dx.doi.org/10.4174/jkss.2011.80.6.412 |
_version_ | 1782215250151473152 |
---|---|
author | Kim, Ho Hyun Park, Eun Kyu Seoung, Jin Shick Hur, Young Hoe Koh, Yang Seok Kim, Jung Chul Cho, Chol Kyoon Kim, Hyun Jong |
author_facet | Kim, Ho Hyun Park, Eun Kyu Seoung, Jin Shick Hur, Young Hoe Koh, Yang Seok Kim, Jung Chul Cho, Chol Kyoon Kim, Hyun Jong |
author_sort | Kim, Ho Hyun |
collection | PubMed |
description | PURPOSE: To analyze the outcomes of laparoscopic liver resection compared with open liver resection in patients with hepatocellular carcinoma (HCC). METHODS: Between July 2005 and December 2009, 26 consecutive patients with HCC underwent a pure laparoscopic liver resection, and data from this group (laparoscopic liver resection group, L-group) were compared with a retrospective control group of 29 patients who underwent open liver resection for HCC (open liver resection group, O-group) during the same period. The two groups were matched in terms of demographic data, tumor size, degree of liver cirrhosis, American Society of Anesthesiology score, type of resection, and tumor location. RESULTS: Median operation time and the amount of intraoperative packed red blood cell transfusion in the L-group were 147.5 minutes and 0.35 units, respectively. The L-group revealed a shorter operation time (147.5 vs. 220.0 minutes, P = 0.031) than the O-group. No difference in perioperative morbidity or mortality rates was observed (3.8, 0 vs. 24.1%, 0%; P = 0.054, non-specific, respectively); the L-group was associated with a shorter hospital stay than the O-group (11.08 vs. 16.07 days, P = 0.034). After a mean follow-up of 23.9 months (range, 0.7 to 59.4 months), the 1-year disease-free survival rate was 84.6% in the L-group and 82.8% in the O-group (P = 0.673). CONCLUSION: Laparoscopic liver resection for HCC is feasible and safe in selected patients and can produce good surgical results with a shorter postoperative hospital stay and similar outcomes in terms of perioperative morbidity, mortality, and disease-free survival than open resection. |
format | Online Article Text |
id | pubmed-3204693 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | The Korean Surgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-32046932011-11-07 Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection Kim, Ho Hyun Park, Eun Kyu Seoung, Jin Shick Hur, Young Hoe Koh, Yang Seok Kim, Jung Chul Cho, Chol Kyoon Kim, Hyun Jong J Korean Surg Soc Original Article PURPOSE: To analyze the outcomes of laparoscopic liver resection compared with open liver resection in patients with hepatocellular carcinoma (HCC). METHODS: Between July 2005 and December 2009, 26 consecutive patients with HCC underwent a pure laparoscopic liver resection, and data from this group (laparoscopic liver resection group, L-group) were compared with a retrospective control group of 29 patients who underwent open liver resection for HCC (open liver resection group, O-group) during the same period. The two groups were matched in terms of demographic data, tumor size, degree of liver cirrhosis, American Society of Anesthesiology score, type of resection, and tumor location. RESULTS: Median operation time and the amount of intraoperative packed red blood cell transfusion in the L-group were 147.5 minutes and 0.35 units, respectively. The L-group revealed a shorter operation time (147.5 vs. 220.0 minutes, P = 0.031) than the O-group. No difference in perioperative morbidity or mortality rates was observed (3.8, 0 vs. 24.1%, 0%; P = 0.054, non-specific, respectively); the L-group was associated with a shorter hospital stay than the O-group (11.08 vs. 16.07 days, P = 0.034). After a mean follow-up of 23.9 months (range, 0.7 to 59.4 months), the 1-year disease-free survival rate was 84.6% in the L-group and 82.8% in the O-group (P = 0.673). CONCLUSION: Laparoscopic liver resection for HCC is feasible and safe in selected patients and can produce good surgical results with a shorter postoperative hospital stay and similar outcomes in terms of perioperative morbidity, mortality, and disease-free survival than open resection. The Korean Surgical Society 2011-06 2011-06-09 /pmc/articles/PMC3204693/ /pubmed/22066068 http://dx.doi.org/10.4174/jkss.2011.80.6.412 Text en Copyright © 2011, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/3.0 Journal of the Korean Surgical Society is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Ho Hyun Park, Eun Kyu Seoung, Jin Shick Hur, Young Hoe Koh, Yang Seok Kim, Jung Chul Cho, Chol Kyoon Kim, Hyun Jong Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection |
title | Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection |
title_full | Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection |
title_fullStr | Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection |
title_full_unstemmed | Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection |
title_short | Liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection |
title_sort | liver resection for hepatocellular carcinoma: case-matched analysis of laparoscopic versus open resection |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204693/ https://www.ncbi.nlm.nih.gov/pubmed/22066068 http://dx.doi.org/10.4174/jkss.2011.80.6.412 |
work_keys_str_mv | AT kimhohyun liverresectionforhepatocellularcarcinomacasematchedanalysisoflaparoscopicversusopenresection AT parkeunkyu liverresectionforhepatocellularcarcinomacasematchedanalysisoflaparoscopicversusopenresection AT seoungjinshick liverresectionforhepatocellularcarcinomacasematchedanalysisoflaparoscopicversusopenresection AT huryounghoe liverresectionforhepatocellularcarcinomacasematchedanalysisoflaparoscopicversusopenresection AT kohyangseok liverresectionforhepatocellularcarcinomacasematchedanalysisoflaparoscopicversusopenresection AT kimjungchul liverresectionforhepatocellularcarcinomacasematchedanalysisoflaparoscopicversusopenresection AT chocholkyoon liverresectionforhepatocellularcarcinomacasematchedanalysisoflaparoscopicversusopenresection AT kimhyunjong liverresectionforhepatocellularcarcinomacasematchedanalysisoflaparoscopicversusopenresection |