Characteristics of Patients with Oseltamivir-Resistant Pandemic (H1N1) 2009, United States

During April 2009–June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant. Most patients with oseltamivir-resistant infections were severely immunocompromised (76%) and had received oseltamivir before specimen collection (...

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Detalles Bibliográficos
Autores principales: Graitcer, Samuel B., Gubareva, Larisa, Kamimoto, Laurie, Doshi, Saumil, Vandermeer, Meredith, Louie, Janice, Waters, Christine, Moore, Zack, Sleeman, Katrina, Okomo-Adhiambo, Margaret, Marshall, Steven A., St. George, Kirsten, Pan, Chao-Yang, LaPlante, Jennifer M., Klimov, Alexander, Fry, Alicia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2011
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204784/
https://www.ncbi.nlm.nih.gov/pubmed/21291599
http://dx.doi.org/10.3201/eid1702.101724
Descripción
Sumario:During April 2009–June 2010, thirty-seven (0.5%) of 6,740 pandemic (H1N1) 2009 viruses submitted to a US surveillance system were oseltamivir resistant. Most patients with oseltamivir-resistant infections were severely immunocompromised (76%) and had received oseltamivir before specimen collection (89%). No evidence was found for community circulation of resistant viruses; only 4 (unlinked) patients had no oseltamivir exposure.

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