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Antigenic, Immunologic and Genetic Characterization of Rough Strains B.abortus RB51, B.melitensis B115 and B.melitensis B18

The lipopolysaccharide (LPS) is considered the major virulent factor in Brucella spp. Several genes have been identified involved in the synthesis of the three LPS components: lipid A, core and O-PS. Usually, Brucella strains devoid of O-PS (rough mutants) are less virulent than the wild type and do...

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Detalles Bibliográficos
Autores principales: Adone, Rosanna, Muscillo, Michele, La Rosa, Giuseppina, Francia, Massimiliano, Tarantino, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204967/
https://www.ncbi.nlm.nih.gov/pubmed/22065984
http://dx.doi.org/10.1371/journal.pone.0024073