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Comparison of Intravenous Medetomidine and Medetomidine/Ketamine for Immobilization of Free-Ranging Variable Flying Foxes (Pteropus hypomelanus)

Medetomidine (0.03 mg/kg) and medetomidine/ketamine (0.05/5.0 and 0.025/2.5 mg/kg), administered by intravenous injection, were evaluated for short-term immobilization of wild-caught variable flying foxes (Pteropus hypomelanus). Medetomidine alone produced incomplete chemical restraint and a stressf...

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Autores principales: Epstein, Jonathan H., Zambriski, Jennifer A., Rostal, Melinda K., Heard, Darryl J., Daszak, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204968/
https://www.ncbi.nlm.nih.gov/pubmed/22065987
http://dx.doi.org/10.1371/journal.pone.0025361
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author Epstein, Jonathan H.
Zambriski, Jennifer A.
Rostal, Melinda K.
Heard, Darryl J.
Daszak, Peter
author_facet Epstein, Jonathan H.
Zambriski, Jennifer A.
Rostal, Melinda K.
Heard, Darryl J.
Daszak, Peter
author_sort Epstein, Jonathan H.
collection PubMed
description Medetomidine (0.03 mg/kg) and medetomidine/ketamine (0.05/5.0 and 0.025/2.5 mg/kg), administered by intravenous injection, were evaluated for short-term immobilization of wild-caught variable flying foxes (Pteropus hypomelanus). Medetomidine alone produced incomplete chemical restraint and a stressful, prolonged induction. Both ketamine/medetomidine doses produced a smooth induction and complete immobilization. The combined medetomidine/ketamine dose of 0.025/2.5 mg/kg produced a rapid induction (232±224 sec) with minimal struggling and vocalization, a complete and effective immobilization period, and tended to lead to a faster and better quality recovery than medetomidine alone or a higher dose of medetomidine and ketamine (0.05/5.0 mg/kg), thus reducing holding time and permitting an earlier release of the bat back into the wild.
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spelling pubmed-32049682011-11-07 Comparison of Intravenous Medetomidine and Medetomidine/Ketamine for Immobilization of Free-Ranging Variable Flying Foxes (Pteropus hypomelanus) Epstein, Jonathan H. Zambriski, Jennifer A. Rostal, Melinda K. Heard, Darryl J. Daszak, Peter PLoS One Research Article Medetomidine (0.03 mg/kg) and medetomidine/ketamine (0.05/5.0 and 0.025/2.5 mg/kg), administered by intravenous injection, were evaluated for short-term immobilization of wild-caught variable flying foxes (Pteropus hypomelanus). Medetomidine alone produced incomplete chemical restraint and a stressful, prolonged induction. Both ketamine/medetomidine doses produced a smooth induction and complete immobilization. The combined medetomidine/ketamine dose of 0.025/2.5 mg/kg produced a rapid induction (232±224 sec) with minimal struggling and vocalization, a complete and effective immobilization period, and tended to lead to a faster and better quality recovery than medetomidine alone or a higher dose of medetomidine and ketamine (0.05/5.0 mg/kg), thus reducing holding time and permitting an earlier release of the bat back into the wild. Public Library of Science 2011-10-31 /pmc/articles/PMC3204968/ /pubmed/22065987 http://dx.doi.org/10.1371/journal.pone.0025361 Text en Epstein et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Epstein, Jonathan H.
Zambriski, Jennifer A.
Rostal, Melinda K.
Heard, Darryl J.
Daszak, Peter
Comparison of Intravenous Medetomidine and Medetomidine/Ketamine for Immobilization of Free-Ranging Variable Flying Foxes (Pteropus hypomelanus)
title Comparison of Intravenous Medetomidine and Medetomidine/Ketamine for Immobilization of Free-Ranging Variable Flying Foxes (Pteropus hypomelanus)
title_full Comparison of Intravenous Medetomidine and Medetomidine/Ketamine for Immobilization of Free-Ranging Variable Flying Foxes (Pteropus hypomelanus)
title_fullStr Comparison of Intravenous Medetomidine and Medetomidine/Ketamine for Immobilization of Free-Ranging Variable Flying Foxes (Pteropus hypomelanus)
title_full_unstemmed Comparison of Intravenous Medetomidine and Medetomidine/Ketamine for Immobilization of Free-Ranging Variable Flying Foxes (Pteropus hypomelanus)
title_short Comparison of Intravenous Medetomidine and Medetomidine/Ketamine for Immobilization of Free-Ranging Variable Flying Foxes (Pteropus hypomelanus)
title_sort comparison of intravenous medetomidine and medetomidine/ketamine for immobilization of free-ranging variable flying foxes (pteropus hypomelanus)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204968/
https://www.ncbi.nlm.nih.gov/pubmed/22065987
http://dx.doi.org/10.1371/journal.pone.0025361
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