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Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27
BACKGROUND: Despite its effectiveness in the treatment of various cancers, the use of doxorubicin is limited by a potentially fatal cardiomyopathy. Prevention of this cardiotoxicity remains a critical issue in clinical oncology. We hypothesized that flavaglines, a family of natural compounds that di...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204970/ https://www.ncbi.nlm.nih.gov/pubmed/22065986 http://dx.doi.org/10.1371/journal.pone.0025302 |