Cargando…
Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27
BACKGROUND: Despite its effectiveness in the treatment of various cancers, the use of doxorubicin is limited by a potentially fatal cardiomyopathy. Prevention of this cardiotoxicity remains a critical issue in clinical oncology. We hypothesized that flavaglines, a family of natural compounds that di...
Autores principales: | Bernard, Yohann, Ribeiro, Nigel, Thuaud, Frédéric, Türkeri, Gülen, Dirr, Ronan, Boulberdaa, Mounia, Nebigil, Canan G., Désaubry, Laurent |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204970/ https://www.ncbi.nlm.nih.gov/pubmed/22065986 http://dx.doi.org/10.1371/journal.pone.0025302 |
Ejemplares similares
-
FL3, a Synthetic Flavagline and Ligand of Prohibitins, Protects Cardiomyocytes via STAT3 from Doxorubicin Toxicity
por: Qureshi, Rehana, et al.
Publicado: (2015) -
Prohibitin Ligands in Cell Death and Survival: Mode of Action and Therapeutic Potential
por: Thuaud, Frédéric, et al.
Publicado: (2013) -
Updates in Anthracycline-Mediated Cardiotoxicity
por: Nebigil, Canan G., et al.
Publicado: (2018) -
Prokineticin Receptor‐1 Is a New Regulator of Endothelial Insulin Uptake and Capillary Formation to Control Insulin Sensitivity and Cardiovascular and Kidney Functions
por: Dormishian, Mojdeh, et al.
Publicado: (2013) -
Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses
por: Nebigil, Canan G., et al.
Publicado: (2020)