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Recurrent DNMT3A R882 Mutations in Chinese Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

Somatic mutations of DNMT3A gene have recently been reported in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). We examined the entire coding sequences of DNMT3A gene by high-resolution melting analysis and sequencing in Chinese patients with myeloid malignancies. R882 mutations wer...

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Detalles Bibliográficos
Autores principales:	Lin, Jiang, Yao, Dong-ming, Qian, Jun, Chen, Qin, Qian, Wei, Li, Yun, Yang, Jing, Wang, Cui-zhu, Chai, Hai-yan, Qian, Zhen, Xiao, Gao-fei, Xu, Wen-rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204995/ https://www.ncbi.nlm.nih.gov/pubmed/22066015 http://dx.doi.org/10.1371/journal.pone.0026906

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