Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

BACKGROUND: Brain-Derived Neurotrophic Factor (BDNF) is the main candidate for neuroprotective therapy for Huntington's disease (HD), but its conditional administration is one of its most challenging problems. RESULTS: Here we used transgenic mice that over-express BDNF under the control of the...

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Detalles Bibliográficos
Autores principales: Giralt, Albert, Carretón, Olga, Lao-Peregrin, Cristina, Martín, Eduardo D, Alberch, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205049/
https://www.ncbi.nlm.nih.gov/pubmed/21985529
http://dx.doi.org/10.1186/1750-1326-6-71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205049/
https://www.ncbi.nlm.nih.gov/pubmed/21985529
http://dx.doi.org/10.1186/1750-1326-6-71

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