Antibodies against Alpha-Synuclein Reduce Oligomerization in Living Cells

Recent research implicates soluble aggregated forms of α-synuclein as neurotoxic species with a central role in the pathogenesis of Parkinson's disease and related disorders. The pathway by which α-synuclein aggregates is believed to follow a step-wise pattern, in which dimers and smaller oligo...

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Detalles Bibliográficos
Autores principales: Näsström, Thomas, Gonçalves, Susana, Sahlin, Charlotte, Nordström, Eva, Screpanti Sundquist, Valentina, Lannfelt, Lars, Bergström, Joakim, Outeiro, Tiago F., Ingelsson, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205056/
https://www.ncbi.nlm.nih.gov/pubmed/22073131
http://dx.doi.org/10.1371/journal.pone.0027230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205056/
https://www.ncbi.nlm.nih.gov/pubmed/22073131
http://dx.doi.org/10.1371/journal.pone.0027230

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